My thumb in my right hand have chronic pain,and do have osteopenia.i am 53 old female.and find difficulty to use my hands the way i was before.

Hand pain: Osteopenia is not likely the cause of pain in your hands. Please see your primary care physician or perhaps a Rheumatologist for further evaluation of possible causes, including several types of arthritis. Don't jump to conclusions about the cause without evaluation.

A few things : may need studies of cervical spine may start with emg MRI exact diagnosis

Osteopenia: Pain in thumb with osteopenia. Likely due to arthritis. If you do have osteopenia this can helped by taking extra vitamin d3