Is tylenol better than advil for headache?

Tylenol: They both may relieve headache. Advil has an additional effect of being anti-inflammatory and Tylenol does not but doesn't irritate the stomach lining or cause fluid retention. Because of this I would favor taking Tylenol if it's effective.

Depends upon the type of headache, but mild tension headaches could respond to either. If a mild migraine, have found Aleve to be more effective than Advil. Tylenol is best in those who have sensitive stomachs.