Possible mets.: Patients with familial adenomatous polyps due to APC mutation gradually develop hundreds colorectal polyps.These may bleed, leading to blood in the stool. Should malignancy develops, this may present with altered bowel habit, or even metastasis to the liver or elsewhere. When the polyposis is associated with osteomas, fibromas, desmoids the condition is termed Gardner's syndrome.
Answered 6/12/2017
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