In general, can a dentist make a removable 2 unit partial denture that will not rest squarely on 2 bone grafted gum areas that are pre-implants?

In General,, : A partial denture may rest on the teeth, the gums or both. Your dentist will tell you if (S)he can make one for you that meets your description. Normally a completely tooth borne partial denture is a bad idea as it can adversely affect the anchor teeth, but perhaps it would be ok as a temporary measure.

Support: Depends on the supporting teeth. Appliance must be designed to be stable and to not stress the stability of the supporting teeth. Your Dentist should be able to design something esthetic, stable, and functional for you.

It can be done: If you have abutments both mesial and distal to the grafted area, it is pretty simple... the appliance will be totally tooth borne. If you do not have a terminal abutment, then an appliance can be fabricated which covers your palate and clasps onto the teeth on the other side of your arch. This may rock when you bite down, creating excess stress on the abutment teeth. Do not wear while eating.

Yes: An Essix appliance can be fabricated that resembles a clear mouth guard with teeth embedded in the appliance where you are missing teeth. The appliance is completely tooth supported and does not have to be in contact with the grafted sites. The Essix is a temporary appliance and not worn when eating.

Probably : Depends on what remaining teeth and where they are. A prosthesis can be designed to fit most any situation. Your dentist can guide you how to achieve this or refer to the appropriate specialist to get you the best results.