A member asked:

Will taking tums or zantac (ranitidine) 150 with advil help prevent stomach irritation/upset caused by advil?

A doctor has provided 1 answer

PPI is better: Over-the-counter proton pump inhibitors like Prilosec (omeprazole) or Nexium (esomeprazole) can protect the stomach from non-steroidal anti-inflammatory drugs (NSAIDs) like Advil (ibuprofen)/Aleve (naproxen). H2 blockers like Zantac (ranitidine)/Pepcid (famotidine) at double dose are less effective, & protect only the duodenum, not the stomach. Antacids like Tums (calcium carbonate) are inadequate for this purpose.

Answered 6/25/2020

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