Is it safe to take sertra 100mg and phentermine 375 together. have had conflicting answers and not sure if it is safe or not?

Safety of both meds: The reason you have heard differing opinions is mixing sertra and Phentermine creates a theoretical risk of a severe & possibly life threatening reaction called seretonin syndrome. I don't believe Phentermine plus an ssri would cause a problem since Phentermine is a noradrenergic agonist. The reason for concern is that fen-phen (no longer on market) rarely caused this due to the Fenfluramine part.

Drug interactions: You can use a drug interaction checker whenever you have questions about drug-drug interactions or drug - food interactions. Here is 1 option (Drugs.Com): https://www.drugs.com/drug_interactions.php Your pharmacist is also a good source of info.