A member asked:

I take methylphenidate 27mg and my dr gave me phentermine 37.5mg for the fatigue from the methylphenidate. is it safe to take these meds together?

3 doctors weighed in across 2 answers

Phentermine/ ritalin (methylphenidate): There is a risk of cardiovascular and CNS stimulatory effects between the two with possible additive toxicity. If you are getting that sleepy on methylphenidate (mp), my practice style would be to have you stop the mp, review for a primary sleep disorder such as sleep apnea as a cause for the adhd. If negative, i would try a different stimulant, one at a time.Or, you could take them and check bp.

Answered 6/10/2014

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Dr. Edward Kuhnley answered

Specializes in Child Psychiatry

Both Phentermine and: Methylphenidate have potential to affect heart rate and blood pressure. The combination may be additive. Use with caution and only as directed by prescriber. Alert prescriber if you experience rapid heart beat or any other adverse effects. They should be safe together in a healthy young person. Best regards.

Answered 11/15/2013

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