U.S. doctors online nowAsk doctors free
Hudson, OH
A 30-year-old male asked:

My doctor has me on doxycycline and cefixime simultaneously to treat lyme disease. much literature and theory suggests that lactams combined with bacteriostatic tetracyclines are antagonistic. is this true for the lyme spirochetes?

2 doctor answers2 doctors weighed in
Dr. John Goldman
Rheumatology 56 years experience
No drug interaction: There is no drug interaction with these 2, There may only be a need for one of these. This depends on the criteria that are used to make the diagnosis. This is the information we need to advise the herapy. You can discuss this with your physician.
Dr. J. Lawrence Dohan
Dermatology 58 years experience
Find a better Dr: You neglected to mention any rationale for this combination. You also failed to define your stage of "Lyme" disease. It matters. Erythema migrans? How was diagnosis made? There are many unfortunate people taking useless antibiotics and herbs for an erroneous diagnosis of "Lyme" disease who actually have something else. Combinations of antibiotics, sometimes a very good idea, are suspicious of char

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Educational text
Talk to a doctor
24/7 visits - just $39!
50% off with $15/month membership
Last updated Nov 27, 2017


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.