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A 27-year-old female asked:

Can i take 100mg zoloft, 75mg wellbutrin, (bupropion) 5mg valium, 10mg zocor, and 8mg zofran on the same day (all prescribed to me)? should i space the doses out?

1 doctor answer2 doctors weighed in
Dr. Edward Kuhnley
Child Psychiatry 46 years experience
Interaction possible: Both Zofran (ondansetron) and Zoloft (sertraline) increase QTc interval of the cardiogram, and both can increase the serotonin effect. These effects may be problematic for some people. Wellbutrin (bupropion) and Zoloft can increase each others' levels which may be problematic. Best to discuss with your prescriber, especially if you experience significant side effects. Best regards for relief.
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Last updated Jul 9, 2016


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