A member asked:

I am taking benadryl (diphenhydramine) with minimal side effects only light sedation. going to try hydroxyzine. will i get more side effects than benadryl (diphenhydramine)?

2 doctors weighed in across 2 answers

Dr. Shadia Constantine answered

Maybe...: I only found one head to head comparison and the study was small. Seems that hydroxyzine has more "anti-itch" effect. The side effects were similar. In a non-scientific website surveying users, seems that Hydroxyzine had more reported side effects. I would like to know what kind of effect are you looking for. They both have some similar and different actions.

Answered 10/10/2017

1.2k views

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Dr. Catherine Spratt turner answered

Hydroxzine: It depends upon the dose you were taking. Benedryl is a antihistamine that is usually very sedating. If you were on a small dose of benedryl and now u You are going on a large dose of Hydroxzine you may have more sedation.

Answered 9/26/2016

1.2k views

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A member asked:

I am taking benadryl (diphenhydramine) with minimal side effects only light sedation. going to try hydroxyzine. will i get more side effects than benadryl (diphenhydramine)?

2 doctors weighed in across 2 answers

Dr. Shadia Constantine answered

Dr. Catherine Spratt turner answered

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