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A 28-year-old male asked:
I am taking benadryl (diphenhydramine) with minimal side effects only light sedation. going to try hydroxyzine. will i get more side effects than benadryl (diphenhydramine)?
2 doctor answers • 2 doctors weighed in

Dr. Shadia Constantineanswered
Specializes in Internal Medicine
Maybe...: I only found one head to head comparison and the study was small. Seems that hydroxyzine has more "anti-itch" effect. The side effects were similar. In a non-scientific website surveying users, seems that Hydroxyzine had more reported side effects. I would like to know what kind of effect are you looking for. They both have some similar and different actions.
Created for people with ongoing healthcare needs but benefits everyone.
1.2k viewsAnswered >2 years ago

Dr. Catherine Spratt turneranswered
Family Medicine 35 years experience
Hydroxzine: It depends upon the dose you were taking. Benedryl is a antihistamine that is usually very sedating. If you were on a small dose of benedryl and now u
You are going on a large dose of Hydroxzine you may have more sedation.
Created for people with ongoing healthcare needs but benefits everyone.
1.2k viewsAnswered >2 years ago
Last updated Oct 10, 2017
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