A member asked:

Generalized itching for five months. no rash, normal blood work no allergies found. zyrtec. benadryl, (diphenhydramine) and hydroxyzine don't work what's wrong with me?

3 doctors weighed in across 2 answers
Dr. Jerome Litt answered

Specializes in Dermatology

GENERALIZED ITCHING: GENERALIZED ITCHING CAN BE DUE TO MANY THINGS: CHANGES IN SOAP OR DETERGENT, CERTAIN MEDICATIONS SUCH AS ANTIBIOTICS, ASPIRIN, OTHER PAIN MEDICATION, PREGNANCY, DIABETES, CHEMICALS, WOOL, FOODS, DRY SKIN, WASHING TOO OFTEN, ECZEMA, PSORIASIS, SCABIES, HIVES, LIVER DISEASE, ANEMIA, AND MUCH MORE. PLEASE SEE YOU PCP OR DERMATOLOGIST. DO NOT WAIT! BEST LUCK

Answered 9/13/2020

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Very difficult: You omitted details. Exactly which blood tests? May be serious. Best see a dermatologist. Never due to laundry products. Not due to food. Only sedation or placebo effect with any antihistamine. Severe, generalized itch with no rash is very difficult to define or treat. Sometimes we find an underlying disease which needs attention. You need a professional, not a DR without experience with this.

Answered 7/29/2015

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