A member asked:

Hydroxyzine and benadryl (diphenhydramine) both give me similar horrible side effects, but doxylamine does not, is there a reason for this?

A doctor has provided 1 answer

Dr. John Chiu answered

Yes: Both Hydroxyzine and Benadryl (diphenhydramine) are highly sedating for people, while doxylamine has less sedating effect. The newer antihistamines have very low or no sedating effects.

Dr Minich agreed

Answered 8/7/2017

4.9k views

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A member asked:

Hydroxyzine and benadryl (diphenhydramine) both give me similar horrible side effects, but doxylamine does not, is there a reason for this?

A doctor has provided 1 answer

Dr. John Chiu answered

Dr Minich agreed

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