A 45-year-old female asked:
Is it safer to take Benadryl (diphenhydramine) or hydroxyzine while taking tramadol 75-100mg?
1 doctor answer
Dr. John Chiu answered
56 years experience in Allergy and Immunology
Neither is better: Since both of the drugs have sedating effects, the choice would depend on which sedates you less or more (depending on your goal). Neither interacts with tramadol otherwise.
Answered on Jul 13, 2014
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