Is it safe to cross taper sertraline 50mg (morning) with 25mg doxepin (night)? if you have previously handled doxepin well ? (stopping sertraline)

?: depends on what you were taking sertraline for? Especially if you were taking it in am I am assuming it was for depression or anxiety. 25 mg doze pin is a very low dose. May help with insomnia. I rarely use it for depression but would take at least 150 mg for therapeutic effect. For some patients using a low dose 25-50 mg 2 or 3 x/d may help anxiety.