A member asked:

Can i make cross tapering zoloft (sertraline) to brintellix?

A doctor has provided 1 answer
Dr. Alan Koenigsberg answered

Specializes in Psychiatry

Probably: The best response is to meet with your prescribing physician and discuss this in detail. In my practice, with my patients, I slowly taper them down on the zoloft (sertraline) about 50mgs weekly, and slowly start them on Brintellix, usually mgs daily for one week, then 10mgs for two weeks, then up to 20mgs daily.

Answered 5/19/2015

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