A member asked:
Would waldenstrom macroglob/mult myeloma definitely show abnormal total protein or abnormal a/g ratio? protein 7.7, alb 4.7, alb 3.0,a/g ratio 1.5
7 doctors weighed in across 2 answers
Not necessarily: About 20% of Multiple myelomas only produce light chains and may not alter serum proteins measurably. There are specific tests for myeloma and Waldenstrom. See this site for more info: http://www.mayoclinic.org/diseases-conditions/multiple-myeloma/basics/definition/con-20026607?mc_id=google&campaign=294429041&geo=9011165&kw=%2Bmyeloma%20%2Bmultiple&ad=90615336761&network=s&sitetarget=&adgroup=21734771441&extension=&target=kwd-30051974370&matchtype=b&device=c&account=1733789621&placementsite=enterprise&gclid=CLec4sjU5swCFYIlgQodY8QHAQ
Answered 11/28/2017
1.3k views
Look for abnormal Pr: Both conditions produce an abnormal Protein in their blood(or sometimes in Urine). This protein is called paraprotein or M spike which can be detected on a test called SPE(Serum Protein Electrophoresis). Once the M spike has been found, then we do a bone marrow test to look for abnormal cells(called Plasma cells which are increased in Myeloma(>10 %) and similar look cells are found in Waldenstrom'
Answered 7/3/2016
1.2k views
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