If zoloft 62mg wasn't very effective would going up to 75mg work better? tried paxil (paroxetine) before and 20mg helped. need safest option for breastfeeding.

Increase is OK: 62mg of Zoloft (sertraline) is unusual as typically this is prescribed in increments of 25mg. Zoloft (sertraline) is considered a relatively safe drug during pregnancy and breastfeeding. The difference between 62 and 75 is minimal, but if you are experiencing depression, try the increase, with consult with your OB/GYB. You cannot equate effective dosages between medications as their metabolic rate is different.