Yes, but....: If you do take Phenergan (promethazine) while on Fluoxetine, it is possible that you can experience excess sedation. You did not list any other medications that you are currently taking. Depending on what else you are on, these interactions can potentially be magnified. Please make sure you keep your doctor informed of all the medications you are taking. Hope this is helpful. All the best.
Answered 7/9/2019
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