Can phenergan (promethazine) cause panic attacks?

No: Promethazine is used to relieve the symptoms of allergic reactions. It is also used with other medications to treat anaphylaxis (sudden, severe allergic reactions) and the symptoms of the common cold such as sneezing, cough, and runny nose. Promethazine can relax and sedate patients before and after surgery, during labor, and at other times. It can be used to prevent & control nausea/vomiting/pain.

Phenergan (promethazine): Common side-effects are dizziness, dry mouth, blurred vision, nausea.