Are there any drug interactions between phenergan, (promethazine) percocet, and pepcid?

Yes: There are definitely drug interactions between Phenergan (promethazine) and Percocet which can lead to drowsiness, mental confusion and others which make operating motor vehicles possibly hazardous, falls possible, nausea to name a few. Be very cautious taking the two together and especially around machinery.

Check it out.: You can use a drug interaction checker whenever you have questions about drug-drug interactions or drug - food interactions. Here is 1 option (Drugs.Com): https://www.drugs.com/drug_interactions.php Your pharmacist is also a good source of info.