I drunk a 8oz mixed drink today around 3pm it is now roughly 1220am is it okay to take benadryl (diphenhydramine) to help me sleep?

Yes: By now virtually all of the alcohol is out of your system so Benadryl (diphenhydramine) is safe to take. However, while Bebadryl is safe to take now and then, I advise not using it regularly. There are many natural alternatives to help sleep, such as magnesium, 5-HTP, valerian, passionflower, skullcap and relaxation techniques. See http://www.drweil.com/drw/u/ART02037/sleep-aid and http://tinyurl.com/jjd47fw