Is it "better" to have sclerotic bone lesions, than lytic ones with bone metases? is there still a greater chance of fracture of the affected bone, whether it is lytic or now sclerotic?

Good question: Excellent question.Unfortunately not an easy answer. But overall, either will do structural damage to the bone and leave it more vulnerable to a fracture or collapse.The lytic ones are quite a bit weaker,however, and can break with little or even no trauma.Both can be very painful and difficult to treat.Also,remember the source: breast,prostate,lung,thyroid, and kidney are more apt to go to bone.