A member asked:

On 1000mg of lithium a day, my blood levels were 0.44 mmol/l (0.3-1.3). last 2 days i'm on 1500mg and still no benefits or side effects. is this weird?

7 doctors weighed in across 3 answers
Dr. Pacita David answered

Specializes in Psychiatry

Not unusual: Lithium levels are affected by a variety of factors, including other medications taken, physiologic states such as dehydration, and kidney functions. Timing of when Lithium is drawn is important. It is generally drawn between 8-12 hours of the last dose. Some formulations are time released, so this can impact results. Levels are used along with clinical findings to guide treatment decisions.

Answered 10/23/2017

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Dr. Krishna Kumar answered

Specializes in Psychiatry

Medication Effects: I understand your need to have relief from your symptoms. Thank you for informing use of Concerta, Aripiprazole, Lamotrigine. You are taking 3 Medications for Bipolar Disorder- Lithium, Aripiprazole, Lamotrigine. All of them and Concerta can affect mood-anxiety to depression. See Psychiatrist for Diagnosis, discontinuing one medication at a time, choose medication needed; follow up; Therapy

Answered 5/3/2018

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Ans: You're taking lithium, Concerta, aripiprazole and Lamotrigine, which interact to cause side effects and make clinical picture hard to understand. Why are you taking two mood stabilizers? Also, Concerta (dose unknown) can trigger mania/hypomania. Hard to interpret lithium level with limited clinical information. Review meds with prescribing doctor to simplify regimen if possible. Hope this helps.

Answered 4/25/2016

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