A member asked:

Have a mutation for immune deficiency (cvid2/igad2) associated with taci. normal iga, igm & igg but long history of severe infections. how to test it?

A doctor has provided 1 answer
Dr. Al Hegab answered

Specializes in Allergy and Immunology

?: Not adding up, you can't literally have those conditions, repeated severe infections and normal measures of Ig subtypes.You need to be re-evaluated, you may simply have IgG subclass deficiency,or specific antibodies deficiency,testing for recall antigens for tetanus and pneumococcus,pre and post vaccination can prove it,treatment remains the same: IVIG therapy.Too complex for this limited platform

Answered 3/22/2020

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