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A member asked:
Hi. first sorry for my english. i was taking 10mg anafranil (clomipramine) for 9 years to control my panic attack and taking 40 mg zedprex for 5 months to control depression. my doctor cut anafranil (clomipramine) last month?
4 doctors weighed in across 2 answers
Why?: there is not enough information in your question to say why he cut it. In general, the principal with medication management is to find the least amount that works. It is OK to ask your doctor why.
Answered 9/6/2015
2.3k views
Probably a wise move: Zedprex may help the panic. Anafranil (clomipramine) & zedprex are classed as serotonin reuptake inhibitors. Some anafranil (clomipramine) converts to norepinephrine reuptake inhibitor in liver via enzyme 2D6. Zedprex slows anafranil (clomipramine) metabolism/conversion. If anafranil (clomipramine) 10 mg was effective, zedprex could make anafranil (clomipramine) ineffective or toxic via altered liver metabolism. If panic recurs call MD or consult halthtap
Answered 11/28/2017
2.3k views
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