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A 54-year-old male asked:
But when it comes to local anaesthetics during ear, nasal or throat surgury, are lidocaine and cocaine interchangable? or is that fair to say, somehow cocaine=lidocaine+epinephrine? thank you very much!
3 doctor answers • 5 doctors weighed in

Dr. Louis Galliaanswered
Surgery - Oral & Maxillofacial 46 years experience
No: No. Different drugs, different indications. OFten used together. Ask your ENT surgeon about what he/she plans to use.
2.5k viewsAnswered >2 years ago

Dr. John Chiuanswered
Allergy and Immunology 58 years experience
Somewhat: Cocaine constricts the blood vessels and thus provides long duration of action (this also is the cause septum perforation for some users). Lidocaine does not constrict the blood vessels and thus epinephrine is usually added in order to prolong its action. They are not interchangeable however.
2.5k viewsReviewed >2 years ago

Dr. Paul Grinanswered
Pain Management 37 years experience
Cocaine or LA w/epi: Because local blocks often require several additional injections, many surgeons prefer general anesthesia or deep sedation.
2.5k viewsReviewed >2 years ago
Last updated Jul 4, 2016
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