A member asked:

Terrible hives&hot flashes.rx'd 10mg zyrtec daily&often take benadryl (diphenhydramine) at bedtime.safe 2gether?what about 20mg zyrtec w benadryl (diphenhydramine)?what else wrks 4 hives

A doctor has provided 1 answer
Dr. Alvin Lin answered

Avoid combination: Both Zyrtec & Benadryl (diphenhydramine) are antihistamines and as such, should not be taken together in same 24hr period due to potential interactions (http://www.drugs.com/interactions-check.php?drug_list=896-1617,569-286). Maximum dose of Zyrtec is 10mg daily so best to avoid exceeding that amount. Check out goo.gl/2dmzkm, goo.gl/v31okZ & http://goo.gl/uYTfTC for more info re chronic urticaria (hives).

Answered 5/17/2015

2.8k views

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Is it safe to take both zyrtec and benadryl (diphenhydramine)?

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Is it safe to take zyrtec and Benadryl (diphenhydramine) at the same time?

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