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A 41-year-old member asked:

I just took zyrtec for hives, can i take benadryl (diphenhydramine) at night?

1 doctor answer2 doctors weighed in
Dr. Franklyn Gergits
ENT and Head and Neck Surgery 31 years experience
Zyrtec ; Benadryl (diphenhydramine): Hello, you can take zyrtec and Benadryl (diphenhydramine) together on the same day. You may notice a little sedation. If so., do not put yourself or anyone else in harm's way.
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Similar questions

A 32-year-old member asked:

Should i take Benadryl (diphenhydramine) until my zyrtec really kicks in?

1 doctor answer3 doctors weighed in
Dr. Brant Ward
Allergy and Immunology 15 years experience
Probably not helpful: Both drugs need to be absorbed by the GI system before they take effect to stop itching and sneezing (can take up to 1 hr). Benadryl (diphenhydramine) can dry up mucus (and make you sleepy), which zyrtec will not do at any time. If you have taken zyrtec for several days without relief from itching or sneezing, you may have something besides allergies (e.g. A cold) or need a different treatment. See your doctor.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated May 16, 2021


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