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A member asked:
Is it safe to take both zyrtec and benadryl (diphenhydramine)?
A doctor has provided 1 answer
Not a good choice: Benadryl (diphenhydramine) is a short acting antihistamine. Zyrtec is a long acting antihistamine. You may overdose if taking both at the same time or taking both in the same day. Consider a better allergy medication if zyrtec is not working well or if you have been taking Benadryl (diphenhydramine) longer than 5 days.
Answered 12/28/2016
5.7k views
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