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A member asked:

Is it safe to take both zyrtec and benadryl (diphenhydramine)?

A doctor has provided 1 answer

Not a good choice: Benadryl (diphenhydramine) is a short acting antihistamine. Zyrtec is a long acting antihistamine. You may overdose if taking both at the same time or taking both in the same day. Consider a better allergy medication if zyrtec is not working well or if you have been taking Benadryl (diphenhydramine) longer than 5 days.

Dr Ali and another doctor agreed

Answered 12/28/2016

5.7k views

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Related Questions

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Is it safe to take Benadryl (diphenhydramine) and Zyrtec together? I was put on Zyrtec for an allergic reaction with steroids for swelling and it's keeping me awake.

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Is it ok to take zyrtec after you've taken benadryl (diphenhydramine)?

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