I have been using 5-htp for six weeks, and i have developed terrible constipation. without laxatives i am unable to do anything. how to treat it?

Fiber and water: The basics; increasing water intake and fiber from fruits and veggies is important. 5 HTP may or may not be related. Too much 5 HTP can actually cause an imbalance in other neurotransmitters, make sure you are under the care of a qualified health practitioner to manage this.

Diet: Any constipation can be treated in many ways. I typically recommend enacting dietary measures such as increasing dietary fiber and decreasing fat. For example, green leafy vegetables and beans are good sources of fiber that may permit stool to be passed. Increasing water and some light exercise is a treatment with little side effect. Exercise is a default therapy for almost any condition.