Usually 36-48 hours: The Augmentin (amoxicillin and clavulanate) starts helping in about 2 days but you may not notice a huge difference in how you feel for up to a week if you had a lot of congestion in the sinuses. Allergies do tend to flare sinuses and sometimes need to be treated with a different med. that Augmentin (amoxicillin and clavulanate) alone wouldn't handle. Nasal irrigation with mild saline can help also
Answered 3/3/2018
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