Try tapering off: Try tapering off nexium (esomeprazole) by taking it every other day for about 2 weeks. You can overlap with Zantac daily as needed during this time frame. If the loose stools persists or is associated with weight loss this could indicate microscopic (lymphocytic colitis) related to chronic nexium (esomeprazole) use. This as well as other possible causes of the diarrhea should then be investigated by your physician.
Answered 5/30/2016
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