Smoke In Their Eyes: Nicotine has a half-life of 1 to 2 hours. Cotinine is an active metabolite of nicotine that remains in the blood for 18 to 20 hours, making it easier to analyze due to its longer half-life. It is excreted in the urine, so drink plenty of fluids. If you are a long-time smoker don't let them take samples of your hair or nails. And make sure they give you a smoking break at the test site.
Answered 6/19/2015
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