Here are some...: There has been no known study on how to use Skelaxin (metaxalone) in patients with kidney disease, which is a very vague concern and so better to refer the concern in the question to kidney function as expressed in GFR. Nonetheless and generally speaking, it is a good practice to take it at less than 400 mg and titrate its dose to clinical response. More? Ask your prescribing doctor.
Answered 2/12/2016
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