A member asked:

I am taking 500mg 5htp per day as instructed by my physician. i have had a bad migraine for 4 days. can i take feverfew and codeine 8mg as well? what else can i do?

3 doctors weighed in across 2 answers
Dr. Julie Abbott answered

Specializes in Preventive Medicine

Probably OK: 5 HTP/5-hydroxytryptophan can be used in the treatment of headaches. Warnings are out there to avoid with some opiates including demerol, (meperidine hydrochloride) but I don't see any specific interaction with codeine. Feverfew seems to interfere with drugs metabolized by the liver; should be ok with 5-HTP. There are probably more effective acute AND preventive migraine medicines to try; ask your doctor. Good wishes:)

Answered 3/17/2015

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Treat vs prevent: General info:5HTP,Feverfew,Butterbur,riboflavin,&magnesium are supplements w variable evidence supporting use for migraine prevention (not acute treatment).In my clinic,best results w latter 3.Acute treatment w NSAIDS or acetaminophen can help,but regular use can CAUSE headaches.Opiates,eg codeine can lead to chronic migraines;use only if instructed by your doc.Headache>72 hrs=call your doc for Rx

Answered 3/18/2015

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