What causes muscle twitches (random body wide) and weak feeling? had for 3 years daily. blood work normal.

Hard to say,,,: This is hard to pinpoint without more of an idea of your daily activities and such. For example, this could easily be due to drinking coffee daily, especially if you're sensitive to it. It might be from stress, like financial and family issues along with those of health. Rarely it can be neurological or muscular, so more info might be needed. It might help to see a neurologist. Best of luck.