A member asked:

I have been on pexola 0.25mg nocte for retless leg syndrome. i have been waking up about 4 or 5 am with severe pain in my lower legs. i usually take a disprin followed by hot milk with honey.

4 doctors weighed in across 2 answers

What's the question?: Restless leg syndrome can be uncomfortable and disruptive to your sleep. to the best of my knowledge, it doesn't cause "severe pain". You need to let your doctor know about this. Circulation problems, muscle spasms and Parkinson's disease can cause leg pain.

Answered 3/9/2015

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Increase dose: I would assume that you are taking Pramipexol, generic name for Pexola. Please, alway provide generic names since trade names are different in different countries. Increase dose of Pramipexol gradually until you can sleep all night - maximum dose is about 2 grams. Obviously, consult your doctor first before making any changes as other medications and/or conditions may effect dosing consideratio

Answered 3/9/2015

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