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A 68-year-old female asked:

I have been on pexola 0.25mg nocte for retless leg syndrome. i have been waking up about 4 or 5 am with severe pain in my lower legs. i usually take a disprin followed by hot milk with honey.

2 doctor answers4 doctors weighed in
Dr. Anne Phelan-adams
A Verified Doctoranswered
A US doctor answeredLearn more
What's the question?: Restless leg syndrome can be uncomfortable and disruptive to your sleep. to the best of my knowledge, it doesn't cause "severe pain". You need to let your doctor know about this. Circulation problems, muscle spasms and Parkinson's disease can cause leg pain.
Dr. Boris Sheynin
Internal Medicine 22 years experience
Increase dose: I would assume that you are taking Pramipexol, generic name for Pexola. Please, alway provide generic names since trade names are different in different countries. Increase dose of Pramipexol gradually until you can sleep all night - maximum dose is about 2 grams. Obviously, consult your doctor first before making any changes as other medications and/or conditions may effect dosing consideratio

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Last updated Mar 9, 2015

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