I've tried many meds for depression but it seems that none help & some make it worse. could i have been misdiagnosed? if so, what could be wrong w/me?

Therapy?: Have you yet tried any form of psychotherapy? Typically, the optimal combination of things to treat emotional issues such as depression is medication (which, on your best day, is supposed to take the edge off symptoms) but the real gruntwork takes place in psychotherapist's consulting room.

Depression: DSM IV has very specific criteria for the diagnosis of depression. you can find them on appropriate websites. the criteria are too long for me to list them here. It is always possible that the diagnosis is incorrect or your brain does not respond well to medications. I would get multiple opinions to make the correct diagnosis and then try different medications.

Depression,: I understand your concern . You are a good human being, Respect yourself.! Stressors in your journey of life including relationships, work, finances, past unresolved conflicts have likely caused emotional turmoil, anxiety, depression, frustration and hopelessness. Please see a Psychiatrist for comprehensive diagnosis, review of all medications and intensive Psychotherapy