Aprox 12 to 15 hours: Lorazepam (Ativan) is readily absorbed with a an absolute bioavailability of 90 percent. Peak concentrations in plasm occur aprox 2 hours after oral administration. The mean half life of unconjugated Lorazepam is about 12-15h ours. Lorezepam is rapidly conjugated to its major metabolite Lorazepam glucuronide 1/2 life 16-20 hr; which has no psychopharm activity and is excreted in urine. avoid bf
Answered 2/5/2015
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