A member asked:

Is ranitidine a ppi?

3 doctors weighed in across 3 answers
Dr. Keshav Narain answered

Specializes in Retinal Surgery

No, H2 blocker: A ppi refers to proton pump inhibitor class of medication. Ranitidine is an h2 blocker and acts via a different mechanism.

Answered 5/22/2019

5.2k views

Thank

No: It is a medication which blocks histamine. Histamine can stimulate the acid producing cells in the stomach to secrete acid. Ppi refers to a different way to decrease stomach acid secretion. They block the cells ability to actually move hydrogen ions out of the cell into the lumen if the stomach.

Answered 5/22/2019

5.2k views

Thank
Dr. Ralph Morgan Lewis answered

Specializes in Family Medicine

No, it's a blocker: Of the histamine-2 receptor, which stimulates gastric acid secretion. Ppi's work by a different mechanism: they irreversibly block the hydrogen/potassium Adenosine triphosphatase enzyme system (the gastric proton pump) of the gastric parietal cells, which secrete acid. Ppi's tend to be stronger inhibitors of acid secretion.

Answered 7/24/2019

5.2k views

Thank

Related Questions

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more