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A member asked:

Is it okay to combine h2 blockers like zantac (ranitidine) with proton pump inhibitors (ppi)?

A doctor has provided 1 answer

Sure, best at night: Some ppi's don't last all day, so acid production rises by evening. Such patients may benefit from either a second dose of ppi medication before dinner, a switch to a longer acting ppi, or the addition of h2 blocker medication at bedtime.

Dr Rosen and another doctor agreed

Answered 10/6/2019

5.7k views

Thank

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Severe acid reflux no matter what I try. Endoscopy showed gastritis but byopsie normal. PPI's made me sick & Zantac (ranitidine) made me dizzy. What can I do?

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I have Barretts. The length has increased from 1cm to 4 as I wasnt taking a PPI. No dysplasia. My GP has prescribed Zantac as she doesnt like PPIs long term. Whats your opinion?

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