High levels of immunoglobulin, does it indicate an illness?

Not usually: Serum immunoglobulins are subdivided into iga, igm, igg, IgD and ige. Ige is the allergic antibody and high levels of this can be seen in allergic conditions and rarely in immune deficiency. High levels of iga, igm, igg are generally thought of as being good as these antibodies protect us from infections. In some rheumatic conditions, immunogloublins can be elevated as a response to inflammation.