A member asked:

What are the treatments for opioid-induced hyperalgesia?

7 doctors weighed in across 3 answers

Tricky: Case reports in the literature have shown success with various pharmacological interventions. Possible treatment regimens include ketamine, dextromethorphan, and nonsteroidal anti-inflammatory drugs (nsaids), opioid switching, amantadine, buprenorphine, α agonists, and methadone.

Answered 3/22/2013

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Dr. Brijesh Chandwani answered

Specializes in Orofacial Pain

Headache specialist: One of the main treatment for opioid-induced hyperalgesia is discontinuing the opioids. You can consult a headache specialist or a pain center for adjunctive management strategies to help too.

Answered 3/21/2013

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Dr. James Henning answered

Specializes in Anesthesiology

Have A Look: ..At this review article below. Oih is a complicated phenomenon and treatment options vary widely in effectiveness...Nsaids, ketamine, opioid withdrawal are all possibilities. In addition, larry chu, md here at stanford is actively involved in researching this issue.. http://www.mendeley.com/catalog/pharmacological-treatment-opioid-induced-hyperalgesia-review-evidence/.

Answered 4/4/2013

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