A 26-year-old female asked:
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do surgical margins matter for benign breast conditions (after excisional biopsy surgery)? would re-excision be necessary if no malignancy is found?

3 doctor answers
Dr. Christian Schultheis
23 years experience Hematology and Oncology
No: If benign, margins are irrelevant. Hope this helps.
Answered on Oct 4, 2016
Dr. Reza Shirazi
19 years experience Radiation Oncology
Possibly yes: Carcinoma insitu, is a pre cancerous lesion, it has the potential of becoming cancer and is treated aggressively. Getting a clear margin around it is a good idea and recommended as it is with malignant lesions. Carcinoma insitu is not benign but it has not grown into a full cancer. Just making sure this is not what you were referring to.
Answered on Nov 27, 2017
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Dr. Andrew Turrisi
46 years experience Radiation Oncology
DCIS has varieties. It causes No Mortality. It heralds invasive cancer. Oncotype unfolding a signature panel that may fulfil what the Van Nuys group and Dr. Silverstein reported, but could not be replicated by others: there is likely a type that needs no further treatment. An ER/PR receptor can and should be done to "guide" use of Tamoxifen/Anastrazole.
Mar 31, 2013
Dr. Christian Schultheis
23 years experience Hematology and Oncology
But DCIS by definition is not a benign condition. Otherwise we would not be treating it.
Mar 19, 2013
Dr. Chad Levitt
21 years experience Radiation Oncology
Yes for some: Dcis needs to be completely removed and the wider the margin the better up to 1 cm. Positive margins should b reexcised. Certain other benign breast lesions likely don't need complete removal always. Negative margin for dcis means 2mm or more.
Answered on Jun 15, 2014
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