Best antibiotic for infection in wound?

Depends : This depends on the location and bacteria causing infection. Most skin / wound infections are gram positive bacteria - so antibiotics to target this is used. If a patient has special circumstances (like immune system issues or certain medical conditions)- he/she is susceptible to uncommon bacteria. Antiobiotic should be tailored to the site and suspected bacteria or cultured bacteria.

No single choice: Choice of antibiotic first requires proving infection and antibiotic sensitivity the choice then depends on specific bacteria or all the different ones present as well as proven sensitivity on culture.