I have hypothyroidism and take synthroid (thyroxine) daily in the a.m. my endo & doc didn't fill & i went through some nasty side effects...normal? anger, weight

Did I understand?: Do you mean you developed symptoms when you didn't take synthroid (thyroxine)? This is possible, but not likely if you just miss a few doses.

Yes,those are normal: Side-effects of hypothyroidism, weight gain, fatigue, lethargy (not anger though) sleepiness, etc. I suggest you see your doctor so they can refill your medication because your period might become too heavy as well.