A member asked:

Hypothyroid treated with synthroid. to test for adren insufficiency (cortisolwas 14), my doc ordered an outpatient metyrapone test. i was instructed to take 12 capsules (250mg) at 11pm with a blood draw at 8am. is this proper dosage or too much?123lb

A doctor has provided 1 answer

Metyrapone: It is generally recommended to give metyrapone 30mg/kg body weight or maximum 2 gms for a person <70Kg weight at around mid-night and then perform blood test in the morning. You are getting the maximum dose 3 gms that is generally given to people who weigh >70 kg. Please discuss it with your doctor.

Answered 10/13/2019

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