What is best medicine to be taken when it was diagnose with moderate hydronephrosis secondary to proximal ureterolithiases?

Lots of fluid: Drinking lots of fluid can help to flush the stone out and relief the blockage and hydronephrosis. However, it depends on the size of the ureterolithiasis. If it is greater than 6mm, a procedure to break up the stone or remove the stone should be considered.

Urologist to advise: Most obsttructing stones in proximal ureter are too large to pass spontaneously, especially if >5mm diameter. Tamsulosin can help to dilate ureter to facilitate passage of kidney stones & drink lots of water. Severe pain would indicate need for intervention with jj stent followed by shockwave or ureteroscopic lithotripsy.