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A member asked:
I had an mthfr test ran and they found a single copy of the c677t but no a1298c. could this be causing my infertility?
5 doctors weighed in across 2 answers
No: Mthfr mutations have been associated with recurrent miscarriage. The linkage is very weak and not even be real. Even if they do, you need to have 2 mutations which you do not. They do not cause infertility.
Answered 3/1/2013
5.3k views
Not so: Mthfr is not a primary cause for infertility. The single copy of 677 does promote less ability to make glutathione and increase inflammation. Consider a supplement called homocysteine factors.
Answered 10/18/2016
5.3k views
Related Questions
A member asked:
I had a miscarage last year at 14 weeks I have mthfr c677t heterozigot pozitive, pai 1 675 and pai 844 heterozigot positive. Could that be the reason?
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Does mthfr heterozygous c677t mutation affect pregnancy?
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A member asked:
Recently diagnosed with MTHFR C677T, have B12 >2000 and high WBC and BP has gone from 90 over 70 to 120 over 78. Chaned diet to Paleo still in pain?
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How low would a patient's protein C activity level has to be before an OB will put her on Lovenox (enoxaparin)? If pt also MTHFR homo C677T, does it change the tx?
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People also searched for:
Im hetero mthfr c677t, husband hetero a1298c. Reason for mult miscarriages? Pregnant again, shld I b taking methylfolate or aspirin or anything else?
My MTHFR gene mutation test says 'not detected' but the note below it says 'this assay detects the mutation C677T in MTHFR' . Does it mean I have it ?
Blood work came back on MTHFR saying I was homozygous for the A1298C mutation and negative for the C677T mutation. Is this anything to worry about?
Should toddler be tested for mthfr if both parents are hetero positive? Mom with c677t, Dad with a1298c. Any benefit/treatment of knwing at young age?
Fertility doctor only sent me a letter with blood results: Lipoprotein (a) 159 mg/dl, Factor VIII 208%, Willebrand-Antigen 220.6%, Willebrand-Activity 211.2%, Heterozygot for MTHFR (C677T and A1298C). Is it serious? What specialist to discuss this?
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