Canada
A 35-year-old female asked:
Im hetero mthfr c677t, husband hetero a1298c. reason for mult miscarriages? pregnant again, shld i b taking methylfolate or aspirin or anything else?
1 doctor answer • 1 doctor weighed in

Dr. John Berrymananswered
Obstetrics and Gynecology 56 years experience
Mthfr genes: Heterozygous individuals pass the mutation to a child 50% of the time. If both parents carry mthfr genes, there is a 1:4 chance that a child will have both, and 1:4 chance of neither (normal). Ask your OB to check your homocysteine level, and folate level, but most with heterozygosity do not need treatment. Only homozygous or a child with both genes may have clotting disorders.
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270 viewsAnswered >2 years ago
Last updated Oct 3, 2018
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