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A 35-year-old female asked:

Im hetero mthfr c677t, husband hetero a1298c. reason for mult miscarriages? pregnant again, shld i b taking methylfolate or aspirin or anything else?

1 doctor answer1 doctor weighed in
Dr. John Berryman
Obstetrics and Gynecology 56 years experience
Mthfr genes: Heterozygous individuals pass the mutation to a child 50% of the time. If both parents carry mthfr genes, there is a 1:4 chance that a child will have both, and 1:4 chance of neither (normal). Ask your OB to check your homocysteine level, and folate level, but most with heterozygosity do not need treatment. Only homozygous or a child with both genes may have clotting disorders.
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Last updated Oct 3, 2018


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